Equipment

The Biomolecular NMR spectroscopy techniques performed at the University of Sheffield provide atomic resolution information on the topology, dynamics and three-dimensional structure of molecules in solution.

A researcher loads a sample into the 800 MHz spectrometer
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We have high-field solution-state NMR spectrometers within the facilit, which are used for a range of biological studies.

600 MHz Bruker Neo 4-channel liquid-state spectrometer

  • Equipped with a high sensitivity TCI cryoprobe with cooled proton and carbon channel and SampleJet automatic sample changer with capacity for over 500 samples.
  • Operating Topspin4.
  • This system was upgraded in 2017 after a research award from the Biotechnology and Biological Sciences Research Council.
600 MHz Bruker Neo 4-channel liquid-state spectrometer

500 MHz Bruker Avance II 3-channel liquid-state spectrometer

  • Equipped with a 5mm TXI probe and 5mm BBO (largely used for 31P NMR).
  • Operating Topspin3.
  • This system was upgraded in May 2019.
500 MHz Bruker Avance II 3-channel liquid-state spectrometer